Pulpa dentis D30 for acute reversible pulpitis: A prospective cohort study in routine dental practice.

dc.contributor.authorHamre, Harald
dc.contributor.authorMittag, Inge
dc.contributor.authorGlockmann, Anja
dc.contributor.authorKiene, Helmut
dc.contributor.authorTröger, Wilfried
dc.date.accessioned2025-02-07T13:37:53Z
dc.date.available2025-02-07T13:37:53Z
dc.date.issued2011
dc.description.abstractBackground: Pulpa dentis D30 (PD: dental pulp of the calf, prepared in a homeopathic D30 potency) has been used in acute reversible pulpitis for pain relief and to avoid or postpone invasive dental treatment. Primary study objective: To study short-term clinical outcomes of PD therapy for acute reversible pulpitis in routine dental practice. Methods/design: Prospective, observational, open-label, single-arm cohort study. Setting: Eleven dental primary care practices in Germany. Participants and intervention: Thirty-two patients starting monotherapy with PD for acute reversible pulpitis without visible or radiological abnormalities. PD was applied as 1-mL submucous injections into the mucobuccal fold, repeated daily as needed. Primary outcome measures: Avoidance of invasive dental treatment (pulp capping, root canal therapy, tooth extraction) and remission of pain, measured on a 0-10 point scale (partial remission: reduction by > or =3 points; complete remission: reduction from > or =4 points to 0-1 points) during the 10-day follow-up period. Results: Median pain duration was 14.0 days. The patients received a median of two PD applications (range 1-7). A total of 81% (n=26/32) of patients did not require invasive dental treatment, and 19% (n= 6) had root canal therapy. Remission status was evaluable in 24 patients. Of these, 63% (n = 15/24) achieved pain remission, 58% (n = 14) remitted without invasive dental treatment (complete remission: n=12, partial remission: n=2), and 29% (n= 7) had a close temporal relationship between PD and remission (ratio "time to remission after first PD application vs pain duration prior to first PD application" <1:10). Conclusion: In this study of PD for acute reversible pulpitis, 58% of evaluable patients achieved pain remission without invasive dental treatment. The open-label pre-post design does not allow for conclusions about comparative effectiveness. However, more than one-fourth of evaluable patients remitted with a close temporal relationship between the first PD application and pain remission, suggesting a causal relationship between therapy and remission.
dc.identifier.citationHamre, H. J., Mittag, I., Glockmann, A., Kiene, H., & Tröger, W. (2011). Pulpa dentis D30 for acute reversible pulpitis: A prospective cohort study in routine dental practice. Alternative Therapies in Health and Medicine, 17(1), 16–21.
dc.identifier.issn1078-6791
dc.identifier.orcidhttps://orcid.org/0000-0003-1098-1079
dc.identifier.other21614940
dc.identifier.urihttps://hdl.handle.net/20.500.14430/762
dc.language.isoen
dc.relation.urlhttps://www.ifaemm.de/publikationen/
dc.subject.meshPulpitis
dc.subject.meshDental Care
dc.subject.meshCohort Studies
dc.subject.meshDental Pulp
dc.subject.meshHomeopathy
dc.subject.meshPain Management
dc.titlePulpa dentis D30 for acute reversible pulpitis: A prospective cohort study in routine dental practice.
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleAltern Ther Health Med
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