Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts -- a case report

dc.contributor.authorWerthmann, Paul G.
dc.contributor.authorSträter, Gregor
dc.contributor.authorFriesland, Hedda
dc.contributor.authorKienle, Gunver S.
dc.date.accessioned2024-05-23T18:54:20Z
dc.date.available2024-05-23T18:54:20Z
dc.date.digitized2021-03-14 20:38:25
dc.date.issued2013
dc.description.abstract<p><strong>Background</strong>: Cutaneous squamous cell carcinoma (CSCC) is a common locally invasive skin cancer which rarely metastasises. First-line treatmentis surgical excision, which is curative in most cases. Viscum album extract (VAE) is a widely used herbal cancer treatment with cytotoxic, apoptogenic and immunological effects, but has not been investigated in CSCC.</p> <p><strong>Case presentation</strong>: A 78-year-old patient with histologically diagnosed CSCC refused surgical excision and was treated with peri-lesional high-dose VAE. After 10 months of treatment the CSCC had disappeared clinically. The patient has been recurrence-free for 4 years.</p> <p><strong>Conclusion</strong>: The presented case shows clinical response of a CSCC to high-dose peri-lesional VAE injections. Further research on VAE in CSCC is warranted.</p> <p><strong>Keywords</strong>: Keywords: Mistletoe, Viscum, Cutaneous squamous cell carcinoma, Case report</p> <p><strong>Citation</strong>: Werthmann, P. G., Sträter, G., Friesland, H., &amp; Kienle, G. S. (2013). Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts – A case report. <em>Phytomedicine</em>, <em>20</em>(3), 324–327. <a href="https://doi.org/10.1016/j.phymed.2012.11.001" target="_blank">https://doi.org/10.1016/j.phymed.2012.11.001</a></p>
dc.description.notesfixed
dc.identifier.citationWerthmann, P. G., Sträter, G., Friesland, H., & Kienle, G. S. (2013). Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts – A case report. Phytomedicine, 20(3), 324–327. https://doi.org/10.1016/j.phymed.2012.11.001
dc.identifier.doihttps://doi.org/10.1016/j.phymed.2012.11.001
dc.identifier.externalUrl/library/2021/3/8/durable-response-of-cutaneous-squamous-cell-carcinoma-following-high-dose-peri-lesional-injections-of-viscum-album-extracts-a-case-report
dc.identifier.urihttps://hdl.handle.net/20.500.14430/435
dc.subject.otherCutaneous squamous cell carcinoma
dc.subject.otherViscum
dc.subject.otherMistletoe
dc.subject.otherCancer
dc.titleDurable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts -- a case report
dspace.entity.typePublication
oaire.citation.titlePhytomedicine
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