Tumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma

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dc.contributor.authorWerthmann, Paul G.
dc.contributor.authorHelling, Dieter
dc.contributor.authorHeusser, Peter
dc.contributor.authorKienle, Gunver S.
dc.date.accessioned2024-05-23T18:54:21Z
dc.date.available2024-05-23T18:54:21Z
dc.date.digitized2021-03-14 20:40:36
dc.date.issued2014
dc.description.abstract<p><strong>SUMMARY</strong><br />Adenoid cystic carcinoma (ACC) is a rare type of cancer that typically originates in the salivary glands. Surgical removal can lead to functional loss and psychological distress. Viscum album extract (VAE) is a herbal remedy with dose-dependent cytotoxic, apoptogenic and immunological effects. In some case reports, tumour regression has been observed following high-dose local applications of VAE. An active 88-year-old man with fast-growing ACC of the hard palate refused surgical removal and received high-dose intratumoural injections of VAE (alone) over a 10-month period. The tumour<br />decreased in size, softened and loosened from its surroundings. A biopsy during the course showed inflammation. The patient remained well and without functional limitations during the therapy and follow-up period (5 months). VAE produced no reported side effects. This aged patient exemplifies a satisfying course of ACC under VAE resulting in good quality of life and partial tumour regression.</p> <p><strong>Citation</strong>: Werthmann, P. G., Helling, D., Heusser, P., &amp; Kienle, G. S. (2014). Tumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma. <em>Case Reports</em>, <em>2014</em>, bcr2013203180. <a href="https://doi.org/10.1136/bcr-2013-203180" target="_blank">https://doi.org/10.1136/bcr-2013-203180</a></p>
dc.description.notesfixed
dc.identifier.citationWerthmann, P. G., Helling, D., Heusser, P., & Kienle, G. S. (2014). Tumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma. Case Reports, 2014, bcr2013203180. https://doi.org/10.1136/bcr-2013-203180
dc.identifier.doihttps://doi.org/10.1136/bcr-2013-203180
dc.identifier.externalUrl/library/2021/3/8/tumour-response-following-high-dose-intratumoural-application-of-viscum-album-on-a-patient-with-adenoid-cystic-carcinoma
dc.identifier.urihttps://hdl.handle.net/20.500.14430/436
dc.subject.otherviscum album
dc.subject.othertumor response
dc.subject.otheradenoid cystic carcinoma
dc.subject.otherCancer
dc.titleTumour response following high-dose intratumoural application of Viscum album on a patient with adenoid cystic carcinoma
dspace.entity.typePublication
oaire.citation.titleBMJ Case Rep
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01 Anthroposophic medicine (AM), therapies and health
02 Case studies in cancer