Immunologic Response to Mistletoe in Cancer Patients [abstract]

dc.contributor.authorGardin, Nilo Esvalter
dc.date.accessioned2024-05-23T18:58:20Z
dc.date.available2024-05-23T18:58:20Z
dc.date.digitized2018-12-31 18:21:48
dc.date.issued2009
dc.description.abstract<p class="" style="white-space:pre-wrap;">European mistletoe (<em>Viscum album</em>) has been used in complementary cancer treatment, but little is known concerning its effects on immunological parameters, although there is evidence that <em>Viscum</em> may stimulate the immune system. In this study, a trial was conducted with cancer patients to determine whether <em>Viscum album</em> extracts could improve the results of immune tests. These were: white blood cell count (leukocytes, neutrophils, lymphocytes), CD4+ and CD8+ T-lymphocytes, intradermal tests of delayed hypersensitivity (candidin, trichophytin, purified protein derivative-PPD), complement C3 and C4, and immunoglobulin A, G and M. Four patients received seven doses of subcutaneous <em>Viscum album</em> 20 mg, twice weekly. Immunological tests were carried out before and after treatment, and an increase in several parameters of humoral and cellular immunity were shown. Apart from reactions around the injection sites, treatment was well tolerated and all patients benefited from it. These results suggest that <em>Viscum album</em> can enhance humoral and cellular immune responses in cancer patients, but further studies attesting to the possible clinical impact of these immunological effects are necessary.</p><p class="" style="white-space:pre-wrap;"><strong>Citation</strong>: Gardin, N. E. (2009). Immunological response to mistletoe (Viscum album L.) in cancer patients: A four-case series. <em>Phytotherapy Research</em>, <em>23</em>(3), 407–411. <a href="https://doi.org/10.1002/ptr.2643" target="_blank">https://doi.org/10.1002/ptr.2643</a></p>
dc.description.notesAbstract
dc.identifier.externalUrl/library/2018/12/31/immunologic-response-to-mistletoe-in-cancer-patients
dc.identifier.urihttps://hdl.handle.net/20.500.14430/604
dc.subject.otherimmune system
dc.subject.otherViscum album
dc.subject.otherMistletoe and immune stimulation
dc.subject.otherMistletoe clinical application
dc.titleImmunologic Response to Mistletoe in Cancer Patients [abstract]
dspace.entity.typePublication
oaire.citation.titlePhytotherapy Research
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