Pilot Study: New Aqueous Extracts of the Mistletoe (Viscum Album L.) Plant, Diminish In Vitro Cell Proliferation of The NSCLC Cell Line with EGFR Mutations HCC 827

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dc.contributor.authorRentea, Razvan
dc.contributor.authorKamsler, Mark
dc.contributor.authorMueller, Malory
dc.date.accessioned2024-05-23T18:56:34Z
dc.date.available2024-05-23T18:56:34Z
dc.date.digitized2023-12-20 14:23:52
dc.date.issued2023
dc.description.abstract<p class="" style="white-space:pre-wrap;">Non-small cell lung adenocarcinoma with EGFR mutations continues to be a vexing problem due to the ability of the cancer to rapidly develop drug resistance. In vitro studies with the non-small cell lung adenocarcinoma cell line HCC827 (with an acquired mutation in the EGFR tyrosine kinase domain, E746 - A750 deletion) are relevant to the finding of increasingly effective treatments. Pharmaceutically processed, extracts of mistletoe, Viscum album Loranthaceae, have been shown since the 1920’s to have potential in cancer therapy. They are currently the most frequently used natural preparations in complementary cancer treatments. In this pilot study we demonstrate that newly prepared standardized extractions of mistletoe (Viscum album, L.), from different host trees, are shown to significantly diminish the cell proliferation of the HCC 827 cell line. </p><p class="" style="white-space:pre-wrap;"><strong>Keywords:</strong> Mistletoe; Viscum album; Iscador; HCC827; non-small cell lung cancer; Adenocarcinoma; EGFR; Extracts; Lili Kolisko; Rudolf Steiner </p><p class="" style="white-space:pre-wrap;">Abbreviations: V: Viscum, NSCLC: Non-Small Cell Lung Cancer; ADC: Adenocarcinoma</p><p class="" style="white-space:pre-wrap;"><strong>External link to article:</strong> https://juniperpublishers.com/ctoij/pdf/CTOIJ.MS.ID.556160.pdf</p>
dc.description.notesfixed
dc.identifier.citationRentea, R., Kamsler, M., & Mueller, M. (2023). Pilot Study: New Aqueous Extracts of the Mistletoe (Viscum Album L.) Plant, Diminish In Vitro Cell Proliferation of The NSCLC Cell Line with EGFR Mutations HCC 827. Cancer Therapy & Oncology International Journal, 25(1). https://doi.org/10.19080/CTOIJ.2023.25.556160
dc.identifier.doihttps://doi.org/10.19080/CTOIJ.2023.25.556160
dc.identifier.externalUrl/library/2023/12/18/pilot-study-new-aqueous-extracts
dc.identifier.urihttps://hdl.handle.net/20.500.14430/520
dc.subject.otherMistletoe
dc.subject.otherViscum album
dc.subject.otherIscador
dc.subject.otherHCC827
dc.subject.otherAdenocarcinoma
dc.subject.otherEGFR
dc.subject.otherExtracts
dc.subject.otherLili Kolisko
dc.subject.otherRudolf Steiner
dc.subject.otherNon-small cell lung cancer
dc.titlePilot Study: New Aqueous Extracts of the Mistletoe (Viscum Album L.) Plant, Diminish In Vitro Cell Proliferation of The NSCLC Cell Line with EGFR Mutations HCC 827
dspace.entity.typePublication
oaire.citation.titleCancer Ther Oncol Int J
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